VERI-5®

Rapid Bacterial Detection in 15 minutes

NANOPLEX® is the basis for the VERI-5® product line commencing with Urinary Tract Infections: addressing over treatment and over-use of antibiotics in hospitals and community settings.

NANOPLEX® enables point-of-care ID and enumeration to rapidly diagnose bacterial infections. Delivering the same quality of information expected from 2-day laboratory tests at the point of care.

The Technology behind NANOPLEX®

Epithelial cells are coated in glycans, simple sugars exploited by pathogens during bacterial infection

We have mimicked this process by engineering a proprietary library of probes capable of recognising target proteins on the surface of the bacteria.

Probes are added directly to the sample and rapidly form glycan-binding complexes with target bacteria.

NANOPLEX® rapidly confirms ID and CFU/ml within 15 minutes.

Disclaimer: Products using NANOPLEX® technology are not CE marked or FDA approved at this time.

The NANOPLEX® Assay

1. Mix

Probes are added directly to the clinical sample

2. Bind

Probes selectively bind to bacterial targets

3. Report

Probes report ID and CFU/ml within 15 minutes

Scientific Publications

BIOCOM 2020 Novel Antimicrobials and AMR Diagnostics- Poster

Glycan functionalisation of latex nanoparticles for detection of Uropathogenic Escherichia coli (UPEC) species

N. Dorh, J. Dorh, M. Kyriakides, JB. Vendeville, J. Preece, Y. Takebayashi, J Samphire, J. Ravier-Soriano, J. Spencer and C. Galan

31st ECCMID 2021 4a Diagnostic Bacteriology & General Microbiology- Poster

Development of a rapid 15-minute test using Glycan-functionalised latex nanoparticles for identification of Uropathogenic Escherichia coli (UPEC) species

M. Kyriakides, JB. Vendeville, J. Preece, H. Newman, A. Mauleon Amieva, M. Holbrow-Wilshaw, S. Medina-Villar, J Samphire, Y. Takebayashi, J. Ravier-Soriano, N. Dorh, J. Spencer, C. Galan and J. Dorh

Eurocarb 2021 21st European Carbohydrate Symposium- Poster [Postponed]

Development of a 15-minute test for Uropathogenic Escherichia coli using Glycan coated microspheres: Eurocarb21 Scientific Program & Abstract Book

JB. Vendeville, M. Kyriakides, J Samphire, J. Ravier-Soriano, A. Mauleon Amieva, M. Holbrow-Wilshaw, H. Newman, S. Medina-Villar, J. Preece, J. Dorh, N. Dorh, and C. Galan.

ACS Biomaterials Science and Engineering 2021- Paper

Fast Identification and Quantification of Uropathogenic E. coli through Cluster Analysis

JB. Vendeville, M. Kyriakides, Takebayashi Y, Rama S, Preece J, Samphire J, Ramos-Soriano J, Mauleon Amieva A, Holbrow-Wilshaw M, Newman H, Lou Kou S, Medina-Villar A, Dorh N, Dorh J, Spencer J and Galan C

Microbiology Society Annual Conference 2022- Poster

Development of a 15-minute test using Glycan functionalised latex microspheres for rapid identification of the 3 most common gram-negative uropathogens

M. Kyriakides, H Newman, S. Rama, JB. Vendeville, J. Preece, M. Holbrow-Wilshaw, T. Robinson, C. Galan, J. Spencer, N. Dorh, and J. Dorh.

BEAM Alliance 7th AMR conference 2023- Poster

Rapid 15-minute test to identify the 3 most common gram-negative uropathogens in Urinary Tract Infections

M. Kyriakides, H Newman, S. Rama, K. Bonney-Bhandal, JB. Vendeville, J. Preece, N. Dorh, and J. Dorh.

BSAC The challenge of Urinary Tract Infections 2023- Poster

Rapid 15-minute test to identity the 3 most common gram-negative uropathogens in Urinary Tract Infections

M. Kyriakides, S. Rama, H Newman, K. Bonney-Bhandal, J. Preece, JB. Vendeville, N. Dorh, and J. Dorh.

Learn more about NANOPLEX®

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